Metabolic & Disease Animal Models

Obesity Models

DIO，ob/ob

Hyperlipidemia Models

High-Fat Diet Hamster

Diet-Induced Obese Mice

MASH Models

GAN/AMLN Diet-Induced,

HFD+CCl₄ (High-Fat Diet + Carbon Tetrachloride),

MCD(Methionine-Choline Deficient Diet)

Metabolic Syndrome Models

ZSF1, ZDSD

Type 2 Diabetes/Obesity

ZDF (Zucker Diabetic Fatty),

ZDSD,

db/db,

ob/ob,

HFD+STZ

Diabetic Nephropathy Models

ZSF1, ZDSD

HFpEF Heart Failure Models

ZSF1

Atherosclerosis Models

ApoE KO

Hypertension Models

SHR, Dahl/SS

International Genetic Standardization (IGS)

Global Consistency: Same genetic background across all Charles River facilities worldwide, refreshed every 3-5 years from core colonies.

Data Reproducibility: Minimizes variability between studies conducted in different locations and times.