• CDX/ PDX Efficacy Screening in Multiple Models

• Efficacy screening for various metabolic and cardiovascular diseases (including diabetes, hypertension, MASH, kidney disease, heart failure, etc.)

• In Vitro ADME

• Efficacy Models for Candidates selection

• In vitro Safety Panel and Off-target Profiling

• PK / PD Evaluation Studies (Bioanalytical methods developed to be GLP-ready)

• Proof-of-concept Disease Model

• Pilot / Exploratory Safety Study

• Tumorigenicity Study

• Abnormal Toxicity Testing

• Hypersensitivity Reaction Testing

• Pre-tox dose-range-finding Studies

• Histopathology and Pathology evaluation

• Clinical Pathology Panels

• Safety Assessment incl. single- and repeat-dose toxicity studies, safety pharmacology, and integrated TK/ PK in GLP toxicology

• Regulatory ready reporting package formatted for IND submissions